I’ve been dragging my feet about writing this article for so long. Not because fish oil isn’t awesome. It is! I’ve been procrastinating, telling myself, “Who doesn’t already know about the importance of fish oil? Everyone’s probably using it already.” In fact, the first time I wrote about it, it was 2009!

Obviously, I came around.

The reality is, you, the person reading this right now, might never have used fish oil before, and might have no clue how important it is for our health.

Or, perhaps you used it for a while, and when you ran out, you didn’t get a refill. You might have been taking fish oil for years, but you’re not using enough to make a difference. Or, you use it consistently but haven’t figured out how to convince your family or friends about why they need to take it too.

Whatever your situation, I’ve got you covered with this article.

Why Is Fish Oil Important?

Fish oil is often advertised for its heart health benefits, but it does so much more than that (not that the health of your heart isn’t important). But I’m getting a little head of myself. Let’s start with a little primer on fish oil, omega-3s, and essential fatty acids, as there’s a lot of confusion out there.

Along with omega-6 fatty acids, omega-3s are part of a special group of fats called essential fatty acids. Like essential amino acids, essential fatty acids are nutrients you need in your diet because your body can’t make them on its own.

You don’t need to give much thought to eating enough omega-6s. They’re prevalent in the diet. Omega-3s…not so much. However, that’s not how things have always been. Long before the days of eating beef and chicken, humans ate a lot more fish, and the average diet was much more balanced with omega-6s and omega-3s.

The imbalance with which we eat those fats today contributes to numerous health problems. But it’s not just about eating less omega-6s. We need more omega-3s in the diet than we consume each day.

Plant foods like flaxseeds, walnuts, soybean, and wheat germ do contain a pretty decent amount of omega-3s, but it isn’t the ideal type of omega-3s for humans. The omega-3 fatty acid in these plants is called alpha-linolenic acid (ALA).

Some animals easily convert ALA to eicosapentaenoic acid (EPA) and docosahexaenoic (DHA). Humans do not. And it’s DHA and EPA that provide the health benefits fish oil is known for.

We need to consume EPA and DHA directly, either by eating fatty fish or through supplementation.

Of course, if you overeat fatty fish, you do risk eating too much mercury. And high-quality fish oil is filtered to virtually eliminate mercury. So your best bet is to eat wild Alaskan salmon once in a while and take high-quality fish oil regularly.

Fish oil is part of my “Foundational Five,” the five supplements I believe everyone needs, and if I had to narrow it down to just two supplements, it would still make the cut.

You’re about to find out why.

An online survey completed by Equation Research showed that only 26 percent of Americans said they take fish oil supplements, even though 63% of the respondents said they felt their diet did not have enough omega-3 fatty acids.

1. Fish Oil Enhances Fat Loss*

If you’re into Keto, you’ve no doubt heard people say, “Eat fat and lose weight.” And while you can eat fat on Keto and drop body fat, most dietary fat doesn’t cause fat loss. It’s the removal of carbs that leads to fat loss.

However, supplementing with omega-3 fatty acids does enhance fat loss, according to research.

Animal research shows that fish oil consumption causes fat loss by stimulating the sympathetic nervous system, which releases noradrenaline. Noradrenaline stimulates brown adipose tissue, raising metabolic rate and heat production. The researchers used high-EPA fish oil at doses of up to 2.4% of the animals total calorie intake. For an adult on a 2000-calorie diet, that would equate to about 5 grams of fish oil per day.

Fish oil seems to be especially useful for reducing visceral, or belly fat.

Since somebody will ask, I’ll address the fact that not all research shows fish oil affects weight loss, but it’s more a case of semantics than bad science. Some studies show that fish oil supplementation doesn’t affect body weight, while still reducing waist-to-hip ratio and visceral fat. In these studies, it’s likely that the fish oil also increased lean body mass while reducing body fat. The scale might not change significantly, but people’s body composition and health risks still do.

A small 2010 study, published in the Journal of the International Society of Sports Nutrition found the following:

Forty-four men and women supplemented with either four grams of safflower oil or four grams of fish oil. Those taking the fish oil decreased body fat and body fat percentage, increased lean body mass, and experienced a decrease in cortisol levels. Interestingly, the study participants were not instructed on diet or exercise. They were encouraged to keep their nutrition and exercise patterns the same as before the study. – Noreen, et al. 2010

That isn’t an excuse to just take fish oil and avoid exercise, but it’s still impressive that the study participants saw the changes they did without any instruction on diet or exercise.

Another reason fish oil helps with fat loss is that it causes fuel partitioning. The omega-3s help your body store more calories as glycogen (stored carbohydrate) rather than as fat.

And one final reason fish oil supports fat loss: It improves satiety. If you stay full longer, you eat less.

2. Fish Oil Supports Healthy Lipids and Blood Glucose*

Though your doctor probably still focuses his or her attention on your total and LDL cholesterol levels, the more important numbers are your triglycerides and HDL

TRIGLYCERIDE/HDL RATIO
RatioRisk Level
1:1 or LessOptimal
2:1Low Risk
3:1Moderate Risk
4:1High Risk

Supplementing with omega-3s has been shown to improve insulin sensitivity, lower triglycerides, and in some studies, improve HDL cholesterol levels.

Blood glucose and triglycerides go hand-in-hand, as you need glucose to build triglycerides. The more sugar in your diet, the higher your triglyceride levels rise. So, it’s no surprise that fish oil supplementation, which has consistently been shown to support normal triglyceride levels, also promotes healthy blood sugar levels and better insulin sensitivity.

Between EPA and DHA, it’s EPA that seems to affect triglycerides the most. And it’s been shown to be effective in adults as well as children.

Fish oil supplementation was shown to lower lipids and glucose in people with nonalcoholic fatty liver disease (NAFLD) as well. Again, not surprising, since high-carbohydrate consumption, especially consumption of fructose, is the most common cause of NAFLD. Yet, it’s rarely recommended for obese patients with metabolic syndrome, who also almost always have NAFLD.

3. Fish Oil Increases Lean Body Mass and Strength*

Research on young and old, exercising and non-exercising adults shows that the addition of fish oil to the diet enhances strength and increases lean body mass. In older adults, it can slow the loss of lean body mass, making it a great complement to a high-protein diet, amino acid supplementation, and other muscle-building supplements.

Of the two most important omega-3s, DHA and EPA, it appears EPA has the most significant effect on protein synthesis.

In research, protein synthesis increased by 30% when fish oil was combined with a sufficient amount of protein or amino acids, compared to amino acids or protein alone! These effects have been shown in healthy young, middle-aged and older men and women.

Muscle growth is a result of increased protein synthesis and/or decreased protein breakdown. The regulation of protein breakdown is controlled by a different process than protein synthesis, and evidence shows that EPA affects both sides of the equation.

Read also: The 4 Best Muscle-Building Supplements For 2018.

4. Fish Oil Supports Healthy Inflammation Levels and Immune Function*

Chronic inflammation is considered one of the leading causes of heart disease. Fish oil protects the heart by supporting healthy levels of inflammation.

In a study that used human blood samples, EPA+DHA intake changed the expression of 1040 genes and resulted in a decreased expression of genes involved in inflammatory and atherogenesis-related pathways.” – Bouwens M, et al. 2009

Imagine that! The habit of taking fish oil every day has a positive effect on more than 1000 genes that regulate inflammation!

Those who do a lot of chronic cardio or large amounts of endurance training should make their omega-3 supplementation a top priority as they’re more likely to experience inflammation.

Inflammation is an immune response, and fish oil not only helps support normal inflammatory levels, but it’s also been shown to support the function of white blood cells.

The endocannabinoid system regulates inflammation. DHA and EPA can be metabolized into cannabinoids, making these omega-3s important for the function of your endocannabinoid system.

Read also: Hemp, Essential Oils, and the Endocannabinoid System: Your Guide.

5. Fish Oil Improves Nutrient Delivery To Cells*

Higher intakes of omega-3s actually change the composition of the cell membrane, allowing nutrients to flow in and out easier. The percentage of omega-3s in the cell membrane can easily be measured through a finger stick blood test.

Not only does fish oil help with nutrient delivery to the cell, but a multivitamin may also improve the assimilation of omega-3s into the cell membrane:

Taking a multivitamin along with fish oil improved the red blood cell’s ability to take up omega-3s into the cell membrane.

Just another example of why the first two supplements for most people should be a high-quality multivitamin and fish oil.

6. Fish Oil Supports Brain Health*

DHA is passed from the mother to her unborn baby, and is crucial for brain development. It then affects brain function throughout life.

Many studies have shown large differences in later development when comparing babies born from mothers who supplemented with fish oil and those who did not. For example, at 2.5 years after birth, toddlers of mothers who supplemented with fish oil had significantly improved hand and eye coordination compared to toddlers of mothers who did not supplement.

The effect of DHA on brain health continues throughout life. Some research indicates DHA could ward off or slow the effects of Alzheimer’s and other cognitive diseases.

7. Additional Benefits Of Fish Oil*

In addition to the benefits mentioned above, fish oil supplementation may:

  • Reduce psychological distress
  • Reduce some symptoms of depression
  • Enhance eye health
  • Improve skin health
  • Possibly reduce the occurrence of infant allergies if used during pregnancy
  • Possibly reduce chest pain (acute coronary syndrome)
  • Reduce age-related sight loss

How Much Fish Oil Should You Eat or Take?

Most of the research showing the benefits mentioned above have participants taking one to two grams of EPA/DHA per day, or two to six fish oil softgels. Conservative recommendations for daily DHA and EPA intake range from one to four grams. Omega-3 softgels vary in their DHA and EPA content, but the label will show you how much is in there.

Lower-quality fish oil supplements usually have about 300 mg of EPA and DHA per 1 gram softgel. Higher quality softgels often have 500-600 mg of EPA and DHA per softgel.

A typical salmon steak provides about one gram of EPA and DHA. Of course, most people do not eat fatty fish, like Wild Alaskan Salmon every day, so supplementation should be a regular part of the diet.

What about the studies that say they don’t work?

In recent years, studies have suggested they may not reduce heart disease risk as once thought. As usual, this is a result of the types of studies used. Also, these studies have only pointed at heart health, not all the other benefits mentioned above.

Observational studies haven’t shown a significant effect at reducing heart disease risk. In such a study, groups of people are asked whether they use fish oil or not. Those who say yes are put in the fish oil group and those who say no are placed in the non-fish oil group. Many of those who say “yes” to taking fish oil say yes because they have fish oil in their cupboards, not because they remember to take them every day.

The other issue with many of these studies is the low dose that’s considered “using fish oil.” When just a gram of fish oil per day, especially low-quality fish oil is used, it’s unlikely to cause many positive effects.

Wrap-Up

Several years ago, my wife Vanessa was in the checkout line at the grocery store. A couple of women were in front of her. One was buying a bottle of fish oil.

The other woman saw the bottle and said, “I heard that fish oil is good for you.”

The woman holding the bottle looked at it, and then looked up at the other woman and said, “I wouldn’t know. My vet told me to get it for my dog.”

Sometimes, we take care of the nutrition needs of our pets better than we do for ourselves. Go ahead and share with your dog, but don’t miss out on the benefits of fish oil for yourself.

CLICK TO GET MY “FOUNDATIONAL FIVE” SUPPLEMENT RECOMMENDATIONS

Show References

Bouwens M. van de Rest 0, Dellschaft N, et al. Fish-oil supplementation induces anti-inflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr. 2009;90(2):415-424

Chilton FH, Dutta R, Reynolds LM, et al. Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases. Nutrients. 2017;9)1):1165. doi: 10.3390/nu9111165.

Davis W. Why does fish oil reduce triglycerides? The Heart Scan Blog. November 1, 2009

Du S, Jin J, Fang W, Su Q. Does Fish Oil Have an Anti-Obesity Effect in Overweight/Obese Adults? A Meta-Analysis of Randomized Controlled Trials. PLoS ONE 10(11): e0142652. doi:10.1371/journal.pone.0142652.

Firlag M, Kamaszewski M, Adamek D, et al. Long-term consumption of fish oil partially protects brain tissue from age-related neurodegeneration. Postepy High Med Dosw. 2015;69:188-196.

Furuhjelm C, Warstedt K, Larsson J, et al. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatrica 2009

Gidding SS, Prospero C, Hossain J., et al. A Double-Blind Randomized Trial of Fish Oil to Lower Triglycerides and Improve Cardiometabolic Risk in Adolescents. J Pediatr. 2014;165(3):497-503.

Gurzell EA, Teague H, Harris M. et al. DHA-enriched fish oil targets B cell lipid microdomains and enhances ex vivo and in vivo B cell function. Journal of Leukocyte Biology, 2012; 93 (4): 463 DOI: 10.1189/jlb.0812394.

Joensen A, Schmidt E, Dethlefsen C, et al. Dietary intake of total marine n-3 polyunstaurated fatty acids, eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid and the risk of acute coronary syndrome – a cohort study. Br J Nutr. 2010;103(4):602-7.

Kim M, Goto T, Yu R, et al. Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system. Sci Rep. 2015;5:18013. 10.1038/srep18013.

Micallef M, Munro I, Garg M. An inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individuals. E J Clin Nutr. 2009:63;1154-1156.

Micallef M, Munro I, Phang M, Garg M. Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity. Br J Nutr. 2009;102(9):1370-1374.

Nutraingredients.com Omega-3 awareness not backed by supplement choices: Survey. Nutraingredients.com. Sept 25, 2009.

Parra D, Ramel A, Bandarra N, et al. A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss. Appetite. 2008;51(3):676-680.

Perricone, N. The Perricone Weight Loss Program. LE Magazine. November, 2005.

Pipingas A, Cockerell R, Grima N, et al. Randomized Controlled Trial Examining the Effects of Fish Oil and Multivitamin Supplementation on the Incorporation of n-3 and n-6 Fatty Acids into Red Blood Cells. Nutrients. 2014;6:1956-1970.

Qin Y, Zhou Y, Chen SH, et al. Fish Oil Supplements Lower Serum Lipids and Glucose in Correlation with a Reduction in Plasma Fibroblast Growth Factor 21 and Prostaglandin E2 in Nonalcoholic Fatty Liver Disease Associated with Hyperlipidemia: A Randomized Clinical Trial. PLoS One. 2015;10(7):e0133496. doi: 10.1371/journal.pone.0133496.

SanGiovanni J, Agron E, Meleth AD, et al. w-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2009;90(6):1601-7.

Smith GI, Atherton P, Reeds DN, et al. Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperaminoacidemia-hyperinsulinemia in healthy young and middle aged men and women. Clin Sci (Long.) 2011;12(6):267-278

Smith GI, Julliand S, Reeds DN. et al. Fish oil–derived n–3 PUFA therapy increases muscle mass and function in healthy older adults. Am J Clin Nutr. 2015;102:115–22

Ulven SM, Holven KB. Comparison of bioavailability of krill oil versus fish oil and health effect. Vascular Health and Risk Management. 2015:11;511–524.

Whalen J. Probing Health Benefits from Eating Omega-3s. The Wall Street Journal. Sept 14, 2009.